BioGenex
is unlocking the power of DNA to revolutionize cancer research and
tumor analysis with the launching this week of its new and improved integrated
eFISHiency System. This complete Laboratory Workflow Solution includes probes,
Detection Systems and Smart Automation for FISH* analysis. FISH is a robust technique
used for the detection of chromosomal aberrations and is invaluable for both
research and diagnosis of solid tumors and hematological malignancies. Until now, cytogenetic laboratories had to
dedicate most of their resources to complicated, time-consuming, manual FISH
staining or had to purchase expensive and large automation systems. With over 1.5 million new cancer
cases per year -there is an urgent need for a small, affordable and accurate
FISH automation system that can save money, and more importantly, help save
lives.
BioGenex eFISHiency
system is the only integrated FISH workflow solution in the market offering an affordable, yet fast and accurate FISH
automation. This system reduces hands-on processing time to less than 30
minutes, has the ability to run up to 10 FISH
protocols simultaneously and provides validated reagents and protocols for
optimal results. The eFISHiency system includes:
·
The
world’s first affordable FISH automation system that fits on a bench-top –
Xmatrx Nano
·
65
highly specific FISH probes
·
FISH
Visualization kits for either FFPE or cell samples
·
Validated
FISH protocols
·
FISH
consumables
·
Performance
guaranteed
BioGenex eFISH probes are processed by a unique Repeat Subtraction
Technique resulting in advanced specificity and improved signal intensity. The
new and improved eFISH kits contain ready-to-use (RTU) protease solutions
(Liquid Pepsin) and improved pre-treatment (EZ-AR2) and post-hybridization
stringency wash solutions. eFISH-Histo kit was specifically developed for fixed
paraffin blocks (FFPE) while eFISH Cyto kit is for cell samples such as bone
marrow aspirate, peripheral blood or cell lines. The DAPI/anti-fade reagent is a
ready-to-use solution for mounting and nuclear counter-staining and was
designed to minimize bleaching of fluorescence dyes during microscopic
evaluation.
BioGenex FISH consumables include positively-charged
barrier slides, coverslips and pipette tips. The unique barrier slides and oil
seal technology effectively form a sealed reaction micro-chamber that prevents
evaporation of micro-reagents during high temperature steps, eliminating the
need for messy rubber cement and thereby reducing set-up time. The reaction
micro-chamber reduces micro-reagent consumption by up to 90% thus reducing
overall cost and eliminating waste.
Professor
Igor Sharakhov, with the Department of Entomology at Virginia Tech, who uses
the Xmatrx system for FISH noted: “[FISH] signal is very bright and very
good…The system produced consistent results and is reliable, especially with
large mapping projects.” By using the Xmatrx, Prof. Sharakhov
was able to allocate time to other tasks around the lab instead of dedicating
talent to manual FISH staining. BioGenex guarantees the performance of their
products throughout their shelf-life and offers premier after-sales support and
service for their eFISHiency system and reagents.
* FISH –
Fluorescent In Situ Hybridization
About BioGenex
BioGenex
designs, develops, and commercializes advanced fully-automated molecular
pathology systems for cancer diagnosis, prognosis, personalized medicine, and
life science research. The recent introduction of our eFISHency integrated
workflow solution for FISH laboratories and miRNA system for characterization
of CUP and for undifferentiated tumors is a game changer that has no rival in
the industry. Our fully-automated molecular pathology workstations are the most
advanced system globally. Our spirit of innovation drives us to deliver cutting
edge technology, years ahead of our competition, and the finest systems for
life Science research and diagnostics.
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